Bay-K-8644(S)-(-)- , 98% , 98625-26-4

Synonym(s):
S-(−)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester

CAS NO.：98625-26-4

Empirical Formula: C16H15F3N2O4

Molecular Weight: 356.3

MDL number:

PRODUCT Properties

• storage temp.: 2-8°C
• solubility: H₂O: slightly soluble
• form: solid
• color: yellow
• Water Solubility: H2O: slightly soluble; ethanol: soluble (Organic solutions are stable for at least 20 days at RT.)
• InChI: 1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1
• InChIKey: ZFLWDHHVRRZMEI-ZDUSSCGKSA-N
• SMILES: COC(=O)C1=C(C)NC(C)=C([C@H]1c2ccccc2C(F)(F)F)[N+]([O-])=O

Description and Uses

(S)-(-)-Bay K8644 has been used as a L-type calcium channel (LTCC) agonist in the suprachiasmatic nucleus (SCN) slices. It has also been used as a LTCC agonist to induce arrhythmia?in rats.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 2933399990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2