BD0678848
2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)aceticacid , 98% , 83881-51-0
CAS NO.：83881-51-0
Empirical Formula: C21H25ClN2O3
Molecular Weight: 388.89
MDL number: MFCD00800721
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB289.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 110-115°C |
| Boiling point: | 542.1±45.0 °C(Predicted) |
| Density | 1.237±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | insoluble in EtOH; ≥122 mg/mL in H2O; ≥19.44 mg/mL in DMSO |
| form | solid |
| pka | 3.46±0.10(Predicted) |
| color | Off-white to light yellow |
| Water Solubility | 101 mg/L |
| InChI | InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26) |
| InChIKey | ZKLPARSLTMPFCP-UHFFFAOYSA-N |
| SMILES | C(O)(=O)COCCN1CCN(C(C2=CC=C(Cl)C=C2)C2=CC=CC=C2)CC1 |
| CAS DataBase Reference | 83881-51-0(CAS DataBase Reference) |
| EPA Substance Registry System | Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- (83881-51-0) |
Description and Uses
Cetirizine is a metabolite of the first-generation H1 antihistamine hydroxyzine. A reduced dosage (5 mg daily) is recommended in patients with chronic renal or hepatic impairment. Sedative side effects increase with dosages of cetirizine >10 mg per day.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
| RTECS | AG0977500 |
| Hazardous Substances Data | 83881-51-0(Hazardous Substances Data) |
