4-(4-(4-Nitrophenyl)-1-piperazinyl)phenol , 97% , 112559-81-6

CAS NO.：112559-81-6

Empirical Formula: C16H17N3O3

Molecular Weight: 299.32

MDL number: MFCD08460988

EINECS: 601-189-8

PRODUCT Properties

• Melting point: >90°C (dec.)
• Boiling point: 540.8±50.0 °C(Predicted)
• Density: 1.317±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• solubility: DMSO (Slightly, Heated)
• pka: 12.18±0.30(Predicted)
• form: Solid
• color: Yellow to Brown
• InChI: InChI=1S/C16H17N3O3/c20-16-7-5-14(6-8-16)18-11-9-17(10-12-18)13-1-3-15(4-2-13)19(21)22/h1-8,20H,9-12H2
• InChIKey: BNHYDULILNJFFY-UHFFFAOYSA-N
• SMILES: C1(O)=CC=C(N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2)C=C1
• CAS DataBase Reference: 112559-81-6(CAS DataBase Reference)

Description and Uses

4-[4-(4-Nitrophenyl)-1-piperazinyl]phenol is a key intermediate in the synthesis of triazole medicines, such as itraconazole (I937500), which are used in curing deep department fungal infections. Inhibitor of endothelial cell proliferation.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319
• Precautionary statements: P261-P305+P351+P338