BD1980448
OmeprazolemetaboliteOmeprazolesulfone , 98% , 88546-55-8
Synonym(s):
5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfonyl]-1H-benzimidazole;5-Methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl}-1H-benzimidazole;Omeprazole sulfone;Omeprazole sulphone
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB418.40 | In Stock |
|
| 250mg | RMB711.20 | In Stock |
|
| 1g | RMB1920.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 80-82°C |
| Boiling point: | 599.3±60.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | ≥40.6 mg/mL in DMSO,≥19.9 mg/mL in EtOH,insoluble in H2O |
| form | Solid |
| pka | 7.97±0.10(Predicted) |
| color | White to off-white |
| BRN | 8347309 |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C17H19N3O4S/c1-10-8-18-15(11(2)16(10)24-4)9-25(21,22)17-19-13-6-5-12(23-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20) |
| InChIKey | IXEQEYRTSRFZEO-UHFFFAOYSA-N |
| SMILES | O=S(C1=NC2=CC(OC)=CC=C2N1)(CC3=NC=C(C)C(OC)=C3C)=O |
Description and Uses
Omeprazole sulfone is the major metabolite of the gastric proton pump inhibitor, omeprazole . It is produced by cytochrome P450 (CYP)3A4 sulfoxidation of esomeprazole and is found in plasma. Omeprazole sulfone has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 18 μM).
A metabolite of Omeprazole.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 2 |
| HS Code | 29333990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 |
