Methylpyrimidine-5-carboxylate , 95% , 34253-01-5

CAS NO.：34253-01-5

Empirical Formula: C6H6N2O2

Molecular Weight: 138.12

MDL number: MFCD06204205

PRODUCT Properties

• Melting point: 76-81 °C
• Boiling point: 224.3±13.0 °C(Predicted)
• Density: 1.213±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• form: solid
• pka: 1.13±0.10(Predicted)
• Appearance: Off-white to yellow Solid
• InChI: 1S/C6H6N2O2/c1-10-6(9)5-2-7-4-8-3-5/h2-4H,1H3
• InChIKey: XMVNUAHPLDBEJH-UHFFFAOYSA-N
• SMILES: COC(=O)c1cncnc1
• CAS DataBase Reference: 34253-01-5

Description and Uses

METHYL PYRIMIDINE-5-CARBOXYLATE is an important electron-deficient heterocyclic organic synthesis intermediate and a versatile molecular building block. It can serve as a key precursor for the development of kinase inhibitors, anticancer agents, antiviral agents, antifungal agents and central nervous system (CNS) drugs. The methoxycarbonyl functional group in its molecular structure can participate in a variety of reaction systems, including ester hydrolysis, reduction, amidation and condensation, and is widely used in the field of pharmaceutical synthesis.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H315-H318-H335
• Precautionary statements: P280-P302+P352-P305+P351+P338+P310
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• HS Code: 2933599590
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Dam. 1; Skin Irrit. 2; STOT SE 3