BD2936948
4,4,4-Trifluoro-3-oxobutanenitrile , 98% , 110234-68-9
| Pack Size | Price | Stock | Quantity |
| 1g | RMB2285.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 43 °C(Press: 2.5 Torr) |
| Density | 1.350±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| pka | 2.74±0.10(Predicted) |
Description and Uses
4,4,4-Trifluoro-3-oxobutanenitrile (cas# 110234-68-9) is used as a reagent in the preparation of ((dimethoxyquinazolinyloxy)phenyl)urea derivatives as orally efficacious inhibitors of V-RAF murine sarcoma viral oncogene. Additionally, it is used as a reagent in preparation of orally active inhibitors of Brahma homolog (BRM)/SMARCA2 ATPase activity for treatment of Brahma related gene 1 (BRG1)/SMARCA4-mutant cancers. It is also used as a reagent in the synthesis of 2-(trifluoromethyl)nicotinic acid derivatives from fluorinated precursors.
Safety
| Symbol(GHS) |   GHS02,GHS06 |
| Signal word | Danger |
| Hazard statements | H225-H301-H315-H319-H335 |
| Precautionary statements | P210-P261-P301+P310-P305+P351+P338 |
| HS Code | 2926907090 |
