cis-2,6-Dimethylmorpholine , 97% , 6485-55-8

CAS NO.：6485-55-8

Empirical Formula: C6H13NO

Molecular Weight: 115.17

MDL number: MFCD00078428

EINECS: 229-353-0

PRODUCT Properties

• Melting point: -85 °C
• Boiling point: 140-142 °C
• Density: 0.93
• vapor pressure: 3.38-5.4hPa at 15.1-21.9℃
• refractive index: 1.445-1.447
• Flash point: 41 °C
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Chloroform (Sparingly), Dichloromethane (Sparingly), Methanol (Slightly)
• form: Liquid
• pka: 9.04±0.60(Predicted)
• color: Clear colorless
• BRN: 878182
• InChI: InChI=1/C6H13NO/c1-5-3-7-4-6(2)8-5/h5-7H,3-4H2,1-2H3/t5-,6+
• InChIKey: HNVIQLPOGUDBSU-OLQVQODUNA-N
• SMILES: N1C[C@H](C)O[C@H](C)C1 |&1:2,5,r|
• LogP: -0.15 at 25℃
• CAS DataBase Reference: 6485-55-8(CAS DataBase Reference)

Description and Uses

Cis-2,6-Dimethylmorpholine is used in the synthesis of p38α MAP kinase inhibitors used in the treatment of autoimmune diseases. Also used towards the synthesis of potent agonists and antagonists of 5-HT 4 receptors.

Safety

• Symbol(GHS): GHS02,GHS05,GHS06,GHS07
• Signal word: Danger
• Hazard statements: H226-H311-H318-H303-H312
• Precautionary statements: P303+P361+P353-P305+P351+P338-P310a-P501a-P210-P233-P240-P241+P242+P243-P280-P302+P352+P312+P361+P364-P305+P351+P338+P310-P370+P378-P403+P235-P405-P501
• Hazard Codes: C,Xn
• Risk Statements: 34-21/22-10-41-37/38-22
• Safety Statements: 45-36/37/39-26-23-39
• RIDADR: 1993
• RTECS: QE1750000
• HazardClass: 3
• PackingGroup: III
• HS Code: 29339900
• Limited Quantities: 5.0 L (1.3 gallons) (liquid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)