tert-Butyl1-amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate , 97% , 756526-06-4

CAS NO.：756526-06-4

Empirical Formula: C23H47NO10

Molecular Weight: 497.62

MDL number: MFCD11041142

PRODUCT Properties

• Boiling point: 544.3±45.0 °C(Predicted)
• Density: 1.067±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C(protect from light)
• solubility: Soluble in Water, DMSO, DCM, DMF
• form: Oil
• pka: 8.74±0.10(Predicted)
• color: Colorless to light yellow
• InChI: InChI=1S/C23H47NO10/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h4-21,24H2,1-3H3
• InChIKey: UMJVFHNJPJVDSB-UHFFFAOYSA-N
• SMILES: C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN

Description and Uses

Amino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

H2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• HS Code: 2942000090