(R)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine , 97% , 908303-26-4

Synonym(s):
(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether;(R)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)]trimethylsilanyloxy)methyl]pyrrolidine;(R)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)]trimethylsilyloxy)methyl]pyrrolidine

CAS NO.：908303-26-4

Empirical Formula: C24H23F12NOSi

Molecular Weight: 597.51

MDL number: MFCD09750448

PRODUCT Properties

• Melting point: 46-55°C
• Boiling point: 382.4±37.0 °C(Predicted)
• Density: 1.319±0.06 g/cm3(Predicted)
• Flash point: >110℃
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• pka: 9.34±0.10(Predicted)
• form: Solid
• color: White to Off-White
• InChIKey: MOHRGTBNEJKFMB-LJQANCHMSA-N
• SMILES: C[Si](C)(C)OC([C@H]1CCCN1)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F

Description and Uses

Catalyst involved in:

• Cyclocondensation of enals with methylenepyrrolidines
• Organocatalytic additions of β-ketosulfoxides to conjugated aldehydes
• Organocatalytic aza-Michael reactions
• Stereoselective propargylic alkylation of propargylic esters with aldehydes
• Epoxidation or aziridination of α,β-unsaturated aldehydes and Feist-Benary reactions of 1,3-dicarbonyls

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3