(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanoltrimethylsilylether , 95% , 848821-61-4

Synonym(s):
(S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether;(S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine;(S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine

CAS NO.：848821-61-4

Empirical Formula: C24H23F12NOSi

Molecular Weight: 597.51

MDL number: MFCD09750447

PRODUCT Properties

• Melting point: 48-56 °C
• Boiling point: 382.4±37.0 °C(Predicted)
• Density: 1.319±0.06 g/cm3(Predicted)
• Flash point: 110 °C
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• form: Solid
• pka: 9.34±0.10(Predicted)
• color: White to Off-White

Description and Uses

(S)-α,α-Bis[3,5-di(trifluoromethyl)phenyl]-O-(trimethylsilyl)pyrrolidine-2-methanol, is a diarylprolinol silyl ether organocatalyst. It is able to catalyze a variety of bond-forming reactions such as C-C, C-N, C-O, C-S, and C-Hal in high yields and excellent levels of enantiocontrol.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3