5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol , 97% , 1054483-78-1

Synonym(s):
2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-Hydroxypyridine-5-boronic acid, pinacol ester

CAS NO.：1054483-78-1

Empirical Formula: C11H16BNO3

Molecular Weight: 221.06

MDL number: MFCD06795671

EINECS: 214-589-6

PRODUCT Properties

• Melting point: 197-198
• Density: 1.10±0.1 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• pka: 11.98±0.10(Predicted)
• form: solid
• color: White
• InChI: 1S/C11H16BNO3/c1-10(2)11(3,4)16-12(15-10)8-5-6-9(14)13-7-8/h5-7H,1-4H3,(H,13,14)
• InChIKey: WAUWXCUPDOXYKS-UHFFFAOYSA-N
• SMILES: CC1(C)OB(OC1(C)C)c2ccc(O)nc2

Description and Uses

6-Hydroxypyridine-3-boronic acid pinacol ester can be used as a reactant:

• In the synthesis of novel glutamate transporter EAAT2 activators.
• To prepare crizotinib derivatives as SHIP2 inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38-38-36
• Safety Statements: 26-36/37/39
• WGK Germany: 2
• HS Code: 2933399990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2