![(4R,12AS)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide](https://img.chemicalbook.com/CAS/20150408/GIF/1335210-35-9.gif)
BD5073241
(4R,12AS)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide , 97% , 1335210-35-9
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB111.20 | In Stock |
|
| 250mg | RMB177.60 | In Stock |
|
| 1g | RMB444.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 684.3±55.0 °C(Predicted) |
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 10.70±0.40(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChIKey | MOSMLVZNRGURDI-BZNIZROVSA-N |
| SMILES | O1CC[C@@H](C)N2C(=O)C3=C(OC)C(=O)C(C(NCC4=CC=C(F)C=C4F)=O)=CN3C[C@]12[H] |
Description and Uses
Dolutegravir intermediate is a new synthetic intermediate of Dolutegravir. Dolutegravir is an integrase inhibitor used to treat human immunodeficiency virus (HIV)-1 infection.
(4R,12AS)-N-(2,4-Difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide is an intermediate in the preparation of dolutegravir, an integrase inhibitor for HIV-1 infection therapy.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 38220090 |
