BD6134248
Hinokiflavone , 98+% , 19202-36-9
CAS NO.：19202-36-9
Empirical Formula: C30H18O10
Molecular Weight: 538.46
MDL number: MFCD00017455
EINECS: 242-877-4
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB2148.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 353-355°C |
| Boiling point: | 841.5±65.0 °C(Predicted) |
| Density | 1.622 |
| storage temp. | 2-8°C |
| solubility | Acetone: Soluble; Chloroform: Soluble; Dichloromethane: Soluble; DMSO: Soluble; Ethyl Acetate: Soluble |
| form | A solid |
| pka | 5.70±0.40(Predicted) |
| color | Light yellow to yellow |
| InChIKey | WTDHMFBJQJSTMH-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=C(O)C=C2)OC2=CC(O)=C(OC3=CC=C(C4OC5=CC(O)=CC(O)=C5C(=O)C=4)C=C3)C(O)=C2C(=O)C=1 |
| LogP | 5.528 (est) |
Description and Uses
Hinokiflavone is a novel modulator of pre-mRNA splicing activity extracted from plants with anti-inflammatory, anti-tumor and antiviral activities. Hinokiflavone is also a potent inhibitor for matrix metalloproteinases (MMPs). Hinokiflavone attenuates the virulence of Methicillin (HY-121544)-resistant staphylococcus aureus by inhibiting caseinolytic protease P (ClpP) with an IC50 value of 34.36 mg/mL. Hinokiflavone induces apoptosis via the reactive oxygen species-mitochondria-mediated apoptotic pathway and inhibits tumor cell migration and invasion. Hinokiflavone is a SUMO protease inhibitor against sentrin-specific protease 1 (SENP1) activity[1][2][3].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P305+P351+P338-P332+P313-P362+P364-P337+P313 |
