BD6209548
Tetrahydroberberine , 98+% , 522-97-4
CAS NO.：522-97-4
Empirical Formula: C20H21NO4
Molecular Weight: 339.39
MDL number: MFCD00067284
EINECS: 208-338-2
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB400.00 | In Stock |
|
| 50mg | RMB640.00 | In Stock |
|
| 100mg | RMB1024.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 166.5 °C |
| Boiling point: | 476.1±45.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: >10 mg/mL, soluble |
| pka | 6.53±0.20(Predicted) |
| form | solid |
| color | yellow |
| biological source | (Corydalis yanhusuo) |
| InChIKey | VZTUIEROBZXUFA-UHFFFAOYSA-N |
| SMILES | N21C(Cc5c(c(c(cc5)OC)OC)C2)c3c(cc4c(c3)OCO4)CC1 |
Description and Uses
Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
| Toxicity | LD50 in mice (mg/kg): 940 orally; 790 s.c.; 100 i.v. (Sadritdinov, Sultanov) |
