BD8809547
3-Phenyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one , 95+% , 18741-24-7
CAS NO.：18741-24-7
Empirical Formula: C14H10N2OS
Molecular Weight: 254.31
MDL number: MFCD00023895
EINECS: 242-550-6
| Pack Size | Price | Stock | Quantity |
| 5g | RMB1680.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 313-314°C |
| Boiling point: | 414.8±28.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| pka | 10.96±0.20(Predicted) |
Description and Uses
PDE7-IN-4 is a phosphodiesterase 7 (PDE7) inhibitor with activity that increases intracellular cyclic adenosine monophosphate (cAMP) levels. PDE7-IN-4 shows potential inhibitory effects in neurotransmission and anti-inflammatory applications. PDE7-IN-4 exerts its biological activity by acting on the cAMP/cAMP response element binding protein (CREB) pathway. The development of PDE7-IN-4 aims to improve its pharmacokinetic characteristics to more effectively target neurodegenerative diseases and other inflammation-related diseases[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2933998090 |
| Toxicity | mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04508, |
