Home Categories (1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione
BD8876255

(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione , 95% , 52328-97-9

Synonym(s):
(E,E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione;Tetramethylcurcumin

CAS NO.:52328-97-9

Empirical Formula: C25H28O6

Molecular Weight: 424.49

MDL number: MFCD19443859

Pack Size Price Stock Quantity
25mg RMB1865.60 In Stock
50mg RMB2798.40 In Stock
100mg RMB4197.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 594.5±50.0 °C(Predicted)
Density  1.140±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: ≥10mg/mL
form  powder
color  yellow
InChI 1S/C25H28O6/c1-25(2,23(26)13-9-17-7-11-19(28-3)21(15-17)30-5)24(27)14-10-18-8-12-20(29-4)22(16-18)31-6/h7-16H,1-6H3/b13-9+,14-10+
InChIKey VMMZAMVBGQWOHT-UTLPMFLDSA-N
SMILES COc1ccc(\C=C\C(=O)C(C)(C)C(=O)\C=C\c2ccc(OC)c(OC)c2)cc1OC

Description and Uses

Tetramethylcurcumin (FLLL31), derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects[1][2].

Safety

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P501
WGK Germany  3
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Chronic 4

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