BD9381347
2,2-Difluoro-1-phenylethanone , 95% , 395-01-7
Synonym(s):
α,α-Difluoroacetophenone;2,2-Difluoro-1-phenylethanone;Difluoromethyl phenyl ketone
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB102.40 | In Stock |
|
| 250mg | RMB170.40 | In Stock |
|
| 1g | RMB430.40 | In Stock |
|
| 5g | RMB1360.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 48-50°C |
| Boiling point: | 53-54°C/12mm |
| Density | 1.180±0.06 g/mL |
| refractive index | 1.4955 |
| Flash point: | 53-54°C/12mm |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | liquid |
| Appearance | Colorless to light yellow Liquid |
| Water Solubility | Immiscible with water. |
| InChI | 1S/C8H6F2O/c9-8(10)7(11)6-4-2-1-3-5-6/h1-5,8H |
| InChIKey | OLYKCPDTXVZOQF-UHFFFAOYSA-N |
| SMILES | FC(F)C(C1=CC=CC=C1)=O |
| CAS DataBase Reference | 395-01-7 |
Description and Uses
2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2914790090 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 |
