BD9487131
3,3-Difluoropyrrolidine hydrochloride , 97% , 163457-23-6
CAS NO.：163457-23-6
Empirical Formula: C4H8ClF2N
Molecular Weight: 143.56
MDL number: MFCD03788948
EINECS: 626-850-8
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB25.60 | In Stock |
|
| 1g | RMB58.40 | In Stock |
|
| 5g | RMB180.00 | In Stock |
|
| 10g | RMB321.60 | In Stock |
|
| 25g | RMB753.60 | In Stock |
|
| 100g | RMB2371.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 128-130°C |
| storage temp. | Inert atmosphere,Room Temperature |
| form | solid |
| color | White to off white |
| Sensitive | Hygroscopic |
| InChI | InChI=1S/C4H7F2N.ClH/c5-4(6)1-2-7-3-4;/h7H,1-3H2;1H |
| InChIKey | YYVPZQADFREIFR-UHFFFAOYSA-N |
| SMILES | N1CCC(F)(F)C1.[H]Cl |
| CAS DataBase Reference | 163457-23-6(CAS DataBase Reference) |
Description and Uses
3,3-Difluoropyrrolidine hydrochloride can be used as a building block in the synthesis of:
- Triazole substituted prolyl difluoropyrrolidines as potential inhibitors of dipeptidyl peptidase-4.
- Dual leucine zipper kinase (DLK) inhibitors.
It can be also used as a reactant in the preparation of cyclic and acyclic β-aminofluoroalkenes via allylic amination using the Pd catalyst.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HazardClass | IRRITANT, HYGROSCOPIC |
| HS Code | 29339900 |
