^b-Cyclodextrin hydrate , Null , 68168-23-0

Synonym(s):
β-Schardinger dextrin;beta-Cyclodextrin hydrate;Cycloheptaamylose;Schardinger β-Dextrin hydrate

CAS NO.：68168-23-0

Empirical Formula: C42H70O35

Molecular Weight: 1134.98

MDL number: MFCD00150811

EINECS: 231-493-2

PRODUCT Properties

• Melting point: >260 °C (dec.)(lit.)
• alpha: 161 º (c=1, H2O 25 ºC)
• storage temp.: Refrigerator
• solubility: Water (Slightly)
• form: Crystalline Powder
• color: White
• optical activity: [α]20/D +142°, c = 1 in H2O (Dry basis)
• Water Solubility: 18.5 g/L (25 ºC)
• Merck: 14,2718
• BRN: 5915513
• InChIKey: WHGYBXFWUBPSRW-JXMPPWEANA-N

Description and Uses

β-Cyclodextrin (β-CD) is a cyclic oligosaccharide that contains seven D-(+)-glucopyranose units and has been used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH₂ groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.

beta-Cyclodextrin hydrate forms clathrates. Produces a water-soluble complex with dansyl chloride for the fluorescent labeling of proteins. It is used in pharmaceutical research, as pharmaceutical intermediates and also as chemical reagents.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
• PPE: Eyeshields, Gloves, type N95 (US)
• Safety Statements: 24/25
• WGK Germany: 2
• RTECS: GU2293000
• TSCA: Yes
• HS Code: 35051000
• Storage Class: 11 - Combustible Solids