LN-034931
PYR-GLU-PRO-NH2 , 99% , 85541-78-2
Update time: 2023-04-23
PRODUCT Properties
| Boiling point: | 899.9±65.0 °C(Predicted) |
| Density | 1.416±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| pka | 4.47±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
Description and Uses
(Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH; HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS[1].
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
| WGK Germany | 3 |
