LN-060334
(R)-2-amino-2-(4-hydroxyphenyl)acetamide , 95% , 54397-23-8
Update time: 2023-04-23
PRODUCT Properties
| storage temp. | -10 to -25°C |
| solubility | Aqueous Acid (Slightly), DMSO (Heated) |
| form | Solid |
| color | White to Pale Red |
| Major Application | pharmaceutical |
| InChI | 1S/C8H10N2O2/c9-7(8(10)12)5-1-3-6(11)4-2-5/h1-4,7,11H,9H2,(H2,10,12)/t7-/m1/s1 |
| InChIKey | WQFROZWIRZWMFE-SSDOTTSWSA-N |
| SMILES | N[C@H](c1ccc(cc1)O)C(=O)N |
Description and Uses
D-p-Hydroxyphenylglycinamide is an activated side chain precursor and is an intermediate in the synthesis of 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (H951260), which is a potential impuritiy of the penicillins, ampicillin and amoxicillin, which have not been reported previously. 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone impurity may be formed during the semi-synthetic preparation of these antibiotics or upon their degradation.
Safety
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
RELATED PRODUCTS
Glycinamide
(2R,4S)-2-((R)-1-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-2-(((R)-2-(((R)-carboxy((2R,4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl)methyl)amino)-1-(4-hydroxyphenyl)-2-oxoethyl)amino)-2-oxoethyl)-5,5-dimethylthiazolidine-4-carboxylicacid(AmoxicillinImpurity)
210289-72-8
210289-72-8
Amoxicillin-d4
(4S)-2-(((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)methyl)-5,5-dimethylthiazolidine-4-carboxylicacid(AmoxicillinImpurity)
1356020-01-3
1356020-01-3
(+)-6-Aminopenicillanic acid
551-16-6
551-16-6