LN-072520
6-(2-PROPENYL)-ERGOLINE-8-CARBOXYLIC ACID , > 95% , 81409-74-7
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | >160oC(dec.) |
| Boiling point: | 530.4±50.0 °C(Predicted) |
| Density | 1.258 |
| storage temp. | Amber Vial, -20°C Freezer |
| solubility | Dioxane (Sparingly), DMSO, Methanol (Sparingly) |
| pka | 3.77±0.20(Predicted) |
| form | Solid |
| color | White to Light Beige to Pale Brown |
| InChI | InChI=1/C18H20N2O2/c1-2-6-20-10-12(18(21)22)7-14-13-4-3-5-15-17(13)11(9-19-15)8-16(14)20/h2-5,9,12,14,16,19H,1,6-8,10H2,(H,21,22)/t12?,14-,16-/s3 |
| InChIKey | YAICYXFUKKMAKO-SSILCPKXNA-N |
| SMILES | [C@]12([H])CC(C(O)=O)CN(CC=C)[C@]1([H])CC1=CNC3=CC=CC2=C13 |&1:0,12,r| |
Description and Uses
6-Allyl-8beta-carboxyergoline is a pharmaceutical intermediate compound used in the preparation of Cabergoline, a drug for the treatment of high levels of prolactin in the blood.
6-Allyl-8β-carboxyergoline is a metabolite of cabergoline (C050000) which is a dopamine D2-receptor agonist.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H302-H362 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P201-P260-P263-P264-P270-P308+P313-P264-P270-P301+P312-P330-P501 |
