MANZAMINE A , 98% , 104196-68-1

CAS NO.：104196-68-1

Empirical Formula: C36H44N4O

Molecular Weight: 548.76

MDL number: MFCD00883806

PRODUCT Properties

• Melting point: ＞240(disassembly)
• Boiling point: 756.6±60.0 °C(Predicted)
• Density: 1.26±0.1 g/cm3(Predicted)
• storage temp.: -20°
• solubility: Soluble in DMSO (up to 25 mg/ml).
• pka: 13.58±0.40(Predicted)
• form: Off white to yellow solid.
• color: Off-White to Pale Yellow
• optical activity: +5020 (CHCl3)
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Description and Uses

Manzamine A (104196-68-1) inhibits vacuolar ATPases and inhibits autophagy in pancreatic cancer cells1. Suppresses atherosclerosis?in vivo2. Manzamine A displays neuritogenic activity3?and suppresses tau hyperphosphorylation in human neuroblastoma cell lines4.

Manzamine A is a β-Carboline alkaloid with anti-inflammatory.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P330-P501