LN-515192
epothilone F , 99.0% , 208518-52-9
Update time: 2023-04-23
PRODUCT Properties
| Boiling point: | 711.3±60.0 °C(Predicted) |
| Density | 1.179±0.06 g/cm3(Predicted) |
| form | Solid |
| pka | 13.15±0.10(Predicted) |
| color | Light yellow to yellow |
Description and Uses
Epothilone F is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.
![(1S,3S,7S,10R,11S,12S,16R)-3-[(1E)-2-[2-(Aminomethyl)-4-thiazolyl]-1-methylethenyl]-7,11-dihydroxy-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione](https://img.chemicalbook.com/CAS/GIF/280578-49-6.gif)
