LN-678434
TacroliMus Methyl Acryl Aldehyde , 0.95 , 109466-74-2
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 68-71°C |
| Boiling point: | 322.1±42.0 °C(Predicted) |
| Density | 1.05±0.1 g/cm3(Predicted) |
| storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 14.46±0.60(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability: | Light Sensitive |
| Major Application | pharmaceutical small molecule |
Description and Uses
Tacrolimus Methyl Acryl Aldehyde is the degradation product of Tacrolimus (F370000), a novel macrocyclic lactone isolated from Streptomyces tsukubaensis, having immunosuppressant activity.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H330-H301-H311 |
| Precautionary statements | P280-P302+P352-P312-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1A |
