LN-687982
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide , 98% , 135729-78-1
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 157-159oC |
| Boiling point: | 439.2±45.0 °C(Predicted) |
| Density | 1.17 |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 14.75±0.20(Predicted) |
| color | White |
Description and Uses
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

![(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide](https://img.chemicalbook.com/CAS/GIF/135729-78-1.gif)
![1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-](https://img.chemicalbook.com/CAS/20180629/GIF/1021456-82-5.gif)



