(R)-Amlodipine , 0.95 , 103129-81-3

CAS NO.：103129-81-3

Empirical Formula: C20H25ClN2O5

Molecular Weight: 408.88

MDL number:

PRODUCT Properties

• Melting point: 101-103°C
• Boiling point: 527.2±50.0 °C(Predicted)
• Density: 1.227±0.06 g/cm3(Predicted)
• storage temp.: -20°C Freezer
• solubility: Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: 8.97±0.10(Predicted)
• color: White to Off-White
• Major Application: pharmaceutical
• InChI: InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m1/s1
• InChIKey: HTIQEAQVCYTUBX-QGZVFWFLSA-N
• SMILES: C1(COCCN)NC(C)=C(C(OC)=O)[C@@H](C2=CC=CC=C2Cl)C=1C(OCC)=O

Description and Uses

(R)-Enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

Safety

• Symbol(GHS): GHS06,GHS08,GHS05,GHS09
• Signal word: Danger
• Hazard statements: H301-H318-H373-H410
• Precautionary statements: P260-P273-P280-P301+P310-P305+P351+P338-P314
• WGK Germany: WGK 3
• Storage Class: 6.1C - Combustible acute toxic Cat.3; toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral; Aquatic Acute 1; Aquatic Chronic 1; Eye Dam. 1; STOT RE 2