METHYL (2R,3S)-(+)-2,3-DIHYDROXY-3-PHENYLPROPIONATE , 0.99 , 122743-18-4

CAS NO.：122743-18-4

Empirical Formula: C10H12O4

Molecular Weight: 196.2

MDL number: MFCD01321380

PRODUCT Properties

• Melting point: 84-88 °C (lit.)
• Boiling point: 345.2±9.0 °C(Predicted)
• Density: 1.266±0.06 g/cm3(Predicted)
• pka: 12.33±0.20(Predicted)
• optical activity: [α]23/D +31°, c = 1 in H2O
• InChI: 1S/C10H12O4/c1-14-10(13)9(12)8(11)7-5-3-2-4-6-7/h2-6,8-9,11-12H,1H3/t8-,9+/m0/s1
• InChIKey: IXDRYSIPXMREGK-DTWKUNHWSA-N
• SMILES: COC(=O)[C@H](O)[C@@H](O)c1ccccc1

Description and Uses

Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate can be used as an intermediate in the synthesis of:

• Biologically important 5-phenyl substituted Δ²-thiazolines.
• An antidepressant, (+)-(S)-dapoxetine.
• (R)-Cyclohexyl lactic acid, a building block required for the preparation of an E-selectin inhibitor.

Safety

• PPE: Eyeshields, Gloves, type N95 (US)
• WGK Germany: 3
• Storage Class: 11 - Combustible Solids