N-ACETYL-L-CYSTEINE METHYL ESTER , 98% (Assay) , 32381-28-5
CAS NO.:32381-28-5
Empirical Formula: C12H20N2O6S2
Molecular Weight: 352.43
MDL number: MFCD00083613
PRODUCT Properties
Melting point: | 77-81 °C |
Boiling point: | 584.5±50.0 °C(Predicted) |
Density | 1.285±0.06 g/cm3(Predicted) |
storage temp. | -15°C |
solubility | DMSO: Soluble: = 10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml |
pka | 13.89±0.46(Predicted) |
Description and Uses
Dimethyl diacetyl cystinate is a derivative of the oxidized dimeric form of cysteine L-cystine (Item No. 31727).1 It inhibits UVB radiation-induced NF-κB nuclear translocation in and IL-1α secretion from HaCaT cells when used at concentrations of 50 or 100 µM. Dimethyl diacetyl cystinate (10 µg/ml) decreases proliferation and IFN-γ and IL-2 secretion in a co-culture of lymphocytes isolated from BALB/c mice and irradiated splenocytes isolated from C57BL/10J mice.2 Subconjunctival administration of dimethyl diacetyl cystinate (8 µg/animal) reduces corneal glutathione (GSH) levels and increases corneal allograft survival in mice.WARNING This product is not for human or veterinary use.