1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester , 90%+ , 21881-78-7

CAS NO.：21881-78-7

Empirical Formula: C21H26N2O6

Molecular Weight: 402.44

MDL number: MFCD00347775

PRODUCT Properties

• Melting point: 123-125℃ (ethanol )
• Boiling point: 512.1±50.0 °C(Predicted)
• Density: 1.186±0.06 g/cm3(Predicted)
• storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: 2.94±0.70(Predicted)
• color: Pale Beige
• Stability: Hygroscopic
• InChI: 1S/C21H26N2O6/c1-11(2)28-20(24)17-13(5)22-14(6)18(21(25)29-12(3)4)19(17)15-8-7-9-16(10-15)23(26)27/h7-12,19,22H,1-6H3
• InChIKey: UPOXKUKUWZYRQV-UHFFFAOYSA-N
• SMILES: CC1=C(C(OC(C)C)=O)C(C(C(OC(C)C)=O)=C(C)N1)C2=CC=CC([N+]([O-])=O)=C2

Description and Uses

3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).

Safety

• WGK Germany: WGK 3
• Storage Class: 11 - Combustible Solids