LN1729153
98% , 27244-64-0
Synonym(s):
2,5-Dihydroxy-L -tyrosine;3-(2,4,5-Trihydroxyphenyl)-L -alanine
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB3072.80 | In Stock |
|
| 250mg | RMB5927.20 | In Stock |
|
| 1g | RMB7682.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >190°C (dec.) |
| Boiling point: | 515.2±38.0 °C(Predicted) |
| Density | 1.606±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated) |
| pka | 2.34±0.25(Predicted) |
| form | Solid |
| color | Brown to Black |
| Stability: | Air Sensitive, Hygroscopic |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C9H11NO5/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11/h2-3,5,11-13H,1,10H2,(H,14,15)/t5-/m0/s1 |
| InChIKey | YLKRUSPZOTYMAT-YFKPBYRVSA-N |
| SMILES | [N+H3][C@@H](Cc1c(cc(c(c1)O)O)O)C(=O)[O-] |
Description and Uses
6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315 |
| Precautionary statements | P264-P270-P280-P301+P312+P330-P332+P313-P501 |
| WGK Germany | WGK 3 |
| HS Code | 2922504500 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Skin Irrit. 2 |
