PRODUCT Properties
| Melting point: | 225-230°C |
| alpha | D19 -85° (c = 0.5 in pyridine) |
| storage temp. | 2-8°C |
| LogP | 2.200 (est) |
Description and Uses
This alkaloid has been isolated by Hoffmann from the bark of Rauwolfia serpentina. It forms colourless crystals from Me2CO and has [α]20D - 82° (c 0.5, pyridine).
Corynanthine is a selective α1-adrenergic receptor antagonist. Corynanthine can significantly lower intraocular pressure in rabbits[1].
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
| Risk Statements | 25 |
| Safety Statements | 1-20-45 |
| RIDADR | 1544 |
| WGK Germany | 3 |
