LN3371749
HNMPA-(AM)3 , ≥98% , 120944-03-8
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB328.00 | In Stock |
|
| 5mg | RMB1388.00 | In Stock |
|
| 10mg | RMB2352.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 573.1±50.0 °C(Predicted) |
| Density | 1.325±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: 15 mg/ml; DMSO: 1 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 1 mg/ml |
| form | Colorless oil. |
| color | Colorless to light yellow |
| InChI | 1S/C20H23O10P/c1-14(21)25-11-28-20(19-9-8-17-6-4-5-7-18(17)10-19)31(24,29-12-26-15(2)22)30-13-27-16(3)23/h4-10,20H,11-13H2,1-3H3 |
| InChIKey | UQODAZKXEREJLZ-UHFFFAOYSA-N |
| SMILES | [P](=O)(OCOC(=O)C)(OCOC(=O)C)C(OCOC(=O)C)c1cc2c(cc1)cccc2 |
Description and Uses
HNMPA-(AM)3 is a cell-permeable and selective insulin receptor tyrosine kinase inhibitor analog of HNMPA. HNMPA-(AM)3 greatly inhibits the ability of prothoracicotropic hormone (PTTH) to activate ERK phosphorylation and stimulate ecdysteroidogenesis. HNMPA-(AM)3 is also effective in inhibiting ecdysteroid production (IC50=14.2 μM) and insulin receptor activity (IC50 is 14.2 μM and 200 μM in mosquitoes and mammals, respectively)[1][2].
Safety
| Symbol(GHS) |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225-H319 |
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 |
| WGK Germany | WGK 1 |
| Storage Class | 10 - Combustible liquids |
