REV5901 , ≥98% , 101910-24-1

Synonym(s):
α-Pentyl-3-[2-quinolinylmethoxy]benzyl alcohol

CAS NO.：101910-24-1

Empirical Formula: C22H25NO2

Molecular Weight: 335.44

MDL number:

PRODUCT Properties

• Boiling point: 497.7±35.0 °C(Predicted)
• Density: 1.123±0.06 g/cm3(Predicted)
• storage temp.: Room temperature
• solubility: ≤100mg/ml in ethanol;100mg/ml in methanol;100mg/ml in acetone;100mg/ml in DMSO;100mg/ml in etonitrile.
• form: Off-white to tan solid.
• pka: 14.48±0.20(Predicted)
• color: white to yellow-brown

Description and Uses

REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a K_i value of 0.7 μM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC₅₀ value of 0.12 μM.

L-655,238 is a potent and selective inhibitor of FLAP (5-LO-activating protein).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3