1,9-Dideoxyforskolin , ≥98% , 64657-18-7
Synonym(s):
7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one;7β-Acetoxy-8,13-epoxy-6β-hydroxy-labd-14-en-11-one;Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem
| Pack Size | Price | Stock | Quantity |
| 500ug | RMB1052.00 | In Stock |
|
| 1mg | RMB1612.00 | In Stock |
|
| 5mg | RMB6392.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 149-150℃ |
| storage temp. | −20°C |
| solubility | methanol: 28 mg/mL |
| form | solid |
| color | white |
| optical activity | [α]26/D +93.6°, c = 6.12 in chloroform(lit.) |
| InChI | 1S/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16?,17-,18-,20-,21+,22-/m0/s1 |
| InChIKey | ZKZMDXUDDJYAIB-OJPJTMFRSA-N |
| SMILES | [H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)C3[C@@]1(C)CCCC2(C)C)C=C |
Description and Uses
Forskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase.
1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H312 |
| Precautionary statements | P280-P302+P352-P312-P322-P363-P501 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
