11-deoxyProstaglandinE2 , ≥98% , 35536-53-9

CAS NO.：35536-53-9

Empirical Formula: C20H32O4

Molecular Weight: 336.47

MDL number: MFCD00797646

PRODUCT Properties

• Boiling point: 510.3±45.0 °C(Predicted)
• Density: 1.085±0.06 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)
• form: A crystalline solid
• pka: 4.75±0.10(Predicted)
• color: White to off-white

Description and Uses

11-deoxy Prostaglandin E₂ (11-deoxy PGE₂) is a stable, synthetic analog of PGE₂ . In contrast to PGE₂ which has bronchodilation effects, 11-deoxy PGE₂ is a powerful bronchoconstrictor and contracts human respiratory tract smooth muscle with potencies ranging from 5 to 30 times higher than PGF_2α .

11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions[1][2].

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H360
• Precautionary statements: P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501