LN4559849
CAY10397 , ≥98% , 78028-01-0
Synonym(s):
5-[[4-(Ethoxycarbonyl)phenyl]azo]-2-hydroxybenzeneacetic acid;CK47A
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB604.00 | In Stock |
|
| 5mg | RMB2436.00 | In Stock |
|
| 10mg | RMB4328.00 | In Stock |
|
| 25mg | RMB9468.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 578.0±50.0 °C(Predicted) |
| Density | 1.29±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | 0.1 M Na2CO3: 200 μg/ml; DMF: 35 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml |
| form | solid |
| pka | 4.05±0.10(Predicted) |
| InChI | 1S/C17H16N2O5/c1-2-24-17(23)11-3-5-13(6-4-11)18-19-14-7-8-15(20)12(9-14)10-16(21)22/h3-9,20H,2,10H2,1H3,(H,21,22)/b19-18+ |
| InChIKey | YYBSDOZYJSGLTH-VHEBQXMUSA-N |
| SMILES | CCOC(=O)c1ccc(cc1)\N=N\c2ccc(O)c(CC(O)=O)c2 |
Description and Uses
Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This enzyme oxidizes the 15-hydroxyl group and hydrogenates the 13,14-double bond, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity. CAY10397 is a selective inhibitor of 15-hydroxy PGDH with an IC50 of approximately 10 μM. CAY10397 acts to prolong the lifetime and activity of endogenously produced prostaglandins both in cell culture and in vivo.[Cayman Chemical]
Safety
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
