UrsodeoxycholicAcid(sodiumsalt) , ≥98%
Pack Size | Price | Stock | Quantity |
250mg | RMB752.00 | In Stock |
|
500mg | RMB1208.00 | In Stock |
|
1g | RMB2120.00 | In Stock |
|
5g | RMB7588.00 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | >185°C (dec.) |
storage temp. | Refrigerator |
solubility | Methanol (Slightly) |
form | Solid |
color | White to Off-White |
Description and Uses
Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; Item No. 10011286).1,2 UDCA is also a metabolite of lithocholic acid (LCA; Item No. 20253) in human liver microsomes.3 It inhibits taurocholic acid (Item No. 16215) uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM.4 UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes.5 Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.WARNING This product is not for human or veterinary use.