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LN4721149

UrsodeoxycholicAcid(sodiumsalt) , ≥98%

CAS NO.:

Empirical Formula: C24H39NaO4

Molecular Weight: 414.55

MDL number: MFCD00065453

Pack Size Price Stock Quantity
250mg RMB752.00 In Stock
500mg RMB1208.00 In Stock
1g RMB2120.00 In Stock
5g RMB7588.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >185°C (dec.)
storage temp.  Refrigerator
solubility  Methanol (Slightly)
form  Solid
color  White to Off-White

Description and Uses

Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; Item No. 10011286).1,2 UDCA is also a metabolite of lithocholic acid (LCA; Item No. 20253) in human liver microsomes.3 It inhibits taurocholic acid (Item No. 16215) uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM.4 UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes.5 Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.WARNING This product is not for human or veterinary use.

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