Home Categories Busulfan-d8
LN4762949

Busulfan-d8 , ≥99% , 116653-28-2

CAS NO.:116653-28-2

Empirical Formula: C6H6D8O6S2

Molecular Weight: 254.35

MDL number: MFCD06658695

Pack Size Price Stock Quantity
1mg RMB644.00 In Stock
5mg RMB2744.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 112-1140C
storage temp.  -20°C Freezer
solubility  DMF: 16.7 mg/ml,DMSO: 16.7 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form  A crystalline solid
color  White to off-white
Major Application pharmaceutical (small molecule)
InChI 1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3/i3D2,4D2,5D2,6D2
InChIKey COVZYZSDYWQREU-SQUIKQQTSA-N
SMILES [S](=O)(=O)(OC(C(C(C(O[S](=O)(=O)C)([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C
CAS Number Unlabeled 55-98-1

Description and Uses

Busulfan-d8 is intended for use as an internal standard for the quantification of busulfan by GC- or LC-MS. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. It forms both intra- and interstrand crosslinks on DNA. In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.

Alkylating agent with antileukemic activity. Antineoplastic

Safety

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H310+H330-H350
Precautionary statements  P201-P202-P260-P262-P264-P270-P271-P280-P284-P301+P310-P330-P302+P352-P304+P340-P308+P313-P320-P361+P364-P403+P233-P405-P501
WGK Germany  WGK 2
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2

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