L-759,633 , ≥98% , 174627-50-0

CAS NO.：174627-50-0

Empirical Formula: C26H40O2

Molecular Weight: 384.59

MDL number: MFCD05662266

PRODUCT Properties

• Boiling point: 447.9±45.0 °C(Predicted)
• Density: 0.956±0.06 g/cm3(Predicted)
• storage temp.: Store at +4°C
• solubility: Ethanol:20.0(Max Conc. mg/mL);52.0(Max Conc. mM); PBS (pH 7.2):0.25(Max Conc. mg/mL);0.65(Max Conc. mM)
• form: Liquid
• color: Colorless to light yellow

Description and Uses

L-759,633 is a high-affinity peripheral cannabinoid receptor (CB₂)-selective agonist with K_i values of 6.4 and 1,043 nM for CB₂ and central cannabinoid (CB₁) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB₂ or CB₁ receptors with IC₅₀ values of 8.1 nM and 10 μM, respectively.

L 759633 is a cannabinoid receptor (CB2) selective agonist and a structural analogues of ??9-Tetrahydro Cannabinol, an active constituent of cannabis. L 759633 has analgesic and anti-inflammatory properties.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H319-H336
• Precautionary statements: P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501