9(S)-HODE(solutioninethanol) , ≥95% , 73543-67-6

Synonym(s):
9S-Hydroxy-10E,12Z-octadecadienoic acid

CAS NO.：73543-67-6

Empirical Formula: C18H32O3

Molecular Weight: 296.44

MDL number: MFCD00065831

EINECS: 804-144-2

PRODUCT Properties

• Boiling point: 416.1±33.0 °C(Predicted)
• Density: 0.970±0.06 g/cm3(Predicted)
• Flash point: 14℃
• storage temp.: -20°C
• solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
• form: ethanol solution (1 mg/mL)
• pka: 4.78±0.10(Predicted)
• color: colorless to light yellow

Description and Uses

9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles.

9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO[1][2].

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H319
• Precautionary statements: P210-P233-P240-P241-P242-P305+P351+P338
• Hazard Codes: F
• Risk Statements: 11
• Safety Statements: 7-16
• RIDADR: UN1170 - class 3 - PG 2 - Ethanol, solution
• WGK Germany: 1