LN7488552
97% , 851067-56-6
| Pack Size | Price | Stock | Quantity |
| 50mg | RMB640.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 682.2±65.0 °C(Predicted) |
| Density | 1.495±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C, protect from light |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly, Heated), DMF (Slightly, Heated) |
| pka | 8.66±0.10(Predicted) |
| form | Solid |
| color | Off-White to Yellow |
| InChIKey | DZCHDINWDGTTBZ-UHFFFAOYSA-N |
| SMILES | C1(NC2=NC=C(N3CCNCC3)C=C2)=NC=C2C(C)=C(Br)C(=O)N(C3CCCC3)C2=N1 |
Description and Uses
6-Desacetyl-6-Bromo Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.
