LoratadineimpurityF , 98% , 125743-80-8

CAS NO.：125743-80-8

Empirical Formula: C22H24ClFN2O2

Molecular Weight: 402.89

MDL number: MFCD00672869

PRODUCT Properties

• Melting point: 149-153 °C
• Boiling point: 490.3±45.0 °C(Predicted)
• Density: 1.29±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• pka: 3.65±0.40(Predicted)
• InChI: InChI=1S/C22H24ClFN2O2/c1-2-28-21(27)26-12-9-17(10-13-26)22(24)19-8-7-18(23)14-16(19)6-5-15-4-3-11-25-20(15)22/h3-4,7-8,11,14,17H,2,5-6,9-10,12-13H2,1H3
• InChIKey: OVPFJWGOZPZTKG-UHFFFAOYSA-N
• SMILES: N1(C(OCC)=O)CCC(C2(F)C3=NC=CC=C3CCC3=CC(Cl)=CC=C32)CC1

Description and Uses

Loratadine Impurity F (Loratadine EP Impurity F; Loratadine USP Related Compound G Impurity) is a fluorinated analog of Loratadine (L469575), which is a nonsedating-type histamine H1-receptor.