17-PhenyltrinorProstaglandinF2αmethylamide , 98% , 155206-01-2

CAS NO.：155206-01-2

Empirical Formula: C24H35NO4

Molecular Weight: 401.54

MDL number:

PRODUCT Properties

• Boiling point: 621.5±55.0 °C(Predicted)
• Density: 1.159±0.06 g/cm3(Predicted)
• storage temp.: -20°C Freezer
• solubility: DMSO (Slightly), Ethanol
• form: Clear Colourless Solution
• pka: 14.25±0.20(Predicted)
• InChIKey: UWIWNJFBNIMMGY-FDBOBMRISA-N
• SMILES: C(NC)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCC1=CC=CC=C1

Description and Uses

17-phenyl trinor Prostaglandin F_2α (17-phenyl trinor PGF_2α) is a metabolically stable analog of PGF_2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF_2α. The ethyl amide of 17-phenyl trinor PGF_2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF_2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.

17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is a stable analog of PGF2α and is a potent agonist of for the FP receptor. Analog of Bimatoprost (B386800), an antiglaucoma agent.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H319
• Precautionary statements: P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501