LN9445658
Spiroxamine , 118134-30-8
Synonym(s):
N-Ethyl-N-propyl-8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-ylmethylamine
| Pack Size | Price | Stock | Quantity |
| 500mg | RMB1820.00 | In Stock |
|
| 1g | RMB2794.40 | In Stock |
|
| 2g | RMB5588.80 | In Stock |
|
| 5g | RMB8377.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | <25 °C |
| Boiling point: | bp 120° at 0.067 hPa |
| Density | 0.96±0.1 g/cm3(Predicted) |
| refractive index | nD20 1.4662 |
| Flash point: | 147 °C |
| storage temp. | 0-6°C |
| solubility | Chloroform: Slightly Soluble |
| pka | 6.9(at 25℃) |
| form | Liquid |
| color | Colorless to light yellow |
| Henry's Law Constant | 4.0×102 mol/(m3Pa) at 25℃, Maniere et al. (2011) |
| Stability: | Hygroscopic |
| Major Application | agriculture environmental |
| InChI | 1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3 |
| InChIKey | PUYXTUJWRLOUCW-UHFFFAOYSA-N |
| SMILES | CCCN(CC)CC1COC2(CCC(CC2)C(C)(C)C)O1 |
| LogP | 4.880 (est) |
| EPA Substance Registry System | Spiroxamine (118134-30-8) |
Description and Uses
Spiroxamine is a tertiary amine fungicide and an inhibitor of Δ14 reductase/Δ8→Δ7 isomerase. It inhibits the growth of N. parvum, B. dothidea, D. seriata, and L. theobromae isolates from grape vines (EC50s = 0.97-10.28 mg/L). Spiroxamine (0.03-30 μM) reduces network formation in rat cortical cultures. It is also cytotoxic to MDA-kb2 cells (EC20 = 9.29 μM).
Spiroxamine is a spiroketalamine fungicide for use on cereal crops. Spiroxamine inhibits ergosterol synthesis. Spiroxamine is used as agricultural fungicide.
Safety
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H317-H361d-H373-H410 |
| Precautionary statements | P273-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313 |
| target organs | Eyes |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn,N |
| Risk Statements | 20/21/22-38-43-50/53 |
| Safety Statements | 36/37/39-46-60-61 |
| RIDADR | UN3082 9/PG 3 |
| WGK Germany | 3 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Repr. 2 Skin Irrit. 2 Skin Sens. 1 STOT RE 2 |
| Toxicity | LD50 in rats (mg/kg): ~595 orally; >1600 dermally; LC50 in rats (mg/m3): ~2772 by inhalation; LC50 (96 hr) in rainbow trout: 18.5 mg/l (Dutzmann) |
