morin , 98% , 480-16-0

Synonym(s):
2′,3,4′,5,7-Pentahydroxyflavone

CAS NO.：480-16-0

Empirical Formula: C15H10O7

Molecular Weight: 302.24

MDL number: MFCD00006826

EINECS: 207-542-9

PRODUCT Properties

• Melting point: 299-300 °C (dec.)(lit.)
• Boiling point: 363.28°C (rough estimate)
• Density: 1.3616 (rough estimate)
• refractive index: 1.4790 (estimate)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: methanol: 50 mg/mL
• form: powder
• Colour Index: 75660
• pka: 6.30±0.40(Predicted)
• color: yellow
• Water Solubility: 0.25g/L(20 ºC)
• Merck: 6269
• Stability: Stable. Incompatible with strong oxidizing agents.
• InChI: 1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
• InChIKey: YXOLAZRVSSWPPT-UHFFFAOYSA-N
• SMILES: O=C1C(O)=C(C(C(O)=C2)=CC=C2O)OC3=CC(O)=CC(O)=C31
• LogP: 1.27-1.54 at 37℃ and pH7.4
• CAS DataBase Reference: 480-16-0(CAS DataBase Reference)
• EPA Substance Registry System: Morin (480-16-0)

Description and Uses

Morin is a natural pentahydroxyflavonol with antioxidant activity. It reduces CD36 expression and oxLDL uptake in U937-derived macrophages, inhibits PIM-1 kinase in vitro (IC50 = 2.7 μM), and reduces the activity of cytochrome P450 isoform 3A4 in liver microsomes. Through these and other actions, morin has anti-oxidant, anti-inflammatory, and other actions in animal models.[Cayman Chemical]

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P301+P310
• Hazard Codes: Xi,T
• Risk Statements: 36/37/38-25
• Safety Statements: 26-36-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• RTECS: LK8749000
• F: 8-10-23
• TSCA: TSCA listed
• HS Code: 29329990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Aquatic Chronic 2
• Toxicity: LD50 intraperitoneal in mouse: 555mg/kg