PF-05175157? , ≥98% , 1301214-47-0

Synonym(s):
1,4-Dihydro-1′-[(2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one;1-Isopropyl-1-(2-methyl-1H-benzo[d]imidazole-6-carbonyl)-1,4-dihydrospiro[indazole-5,4-piperidin]-7(6H)-one

CAS NO.：1301214-47-0

Empirical Formula: C23H27N5O2

Molecular Weight: 405.49

MDL number:

PRODUCT Properties

• Boiling point: 692.0±55.0 °C(Predicted)
• Density: 1.38±0.1 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: DMSO:20.0(Max Conc. mg/mL);49.38(Max Conc. mM)
• form: A crystalline solid
• pka: 11.47±0.10(Predicted)
• color: White to off-white
• InChI: 1S/C23H27N5O2/c1-14(2)28-21-17(13-24-28)11-23(12-20(21)29)6-8-27(9-7-23)22(30)16-4-5-18-19(10-16)26-15(3)25-18/h4-5,10,13-14H,6-9,11-12H2,1-3H3,(H,25,26)
• InChIKey: BDXXSFOJPYSYOC-UHFFFAOYSA-N
• SMILES: CC(C)N(N=C1)C2=C1CC3(CCN(C(C4=CC(NC(C)=N5)=C5C=C4)=O)CC3)CC2=O

Description and Uses

PF-05175157 has been used as an acetyl-Coenzyme A carboxylase (ACC) inhibitor to study its effects on the infection of flavivirus.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• WGK Germany: WGK 3
• Storage Class: 11 - Combustible Solids