Propargyl-peg3-bromide , 95% , 203740-63-0

CAS NO.：203740-63-0

Empirical Formula: C9H15BrO3

Molecular Weight: 251.12

MDL number: MFCD28505517

PRODUCT Properties

• Boiling point: 287.8±25.0 °C(Predicted)
• Density: 1.300±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C, stored under nitrogen, away from moisture
• solubility: Soluble in DMSO, DCM, DMF
• form: Liquid
• color: Colorless to light yellow

Description and Uses

Propargyl-PEG3-bromide comprises a propargyl group and a bromide group. The propargyl group reacts with azide-bearing compounds or biomolecules in Click Chemistry to yield a stable triazole linkage; copper will be needed as a catalyst.

Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
• HS Code: 2942000090