M7477858
Bromo-peg5-acid , 98% , 1817735-27-5
CAS NO.：1817735-27-5
Empirical Formula: C13H25BrO7
Molecular Weight: 373.24
MDL number: MFCD29042374
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB880.00 | In Stock |
|
| 1g | RMB1920.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 462.1±45.0 °C(Predicted) |
| Density | 1.320±0.06 g/cm3(Predicted) |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Description and Uses
Bromo-PEG5-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302-H314 |
| Precautionary statements | P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501 |
