PRODUCT Properties
| Melting point: | 244 °C (decomp)(Solv: methanol (67-56-1)) |
| Boiling point: | 538.3±50.0 °C(Predicted) |
| Density | 1.402±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 20.83 mg/mL (66.28 mM);Water : < 0.1 mg/mL (insoluble) |
| pka | 6.49±0.40(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
| InChI | InChI=1S/C17H14O6/c1-21-13-4-3-9(5-15(13)22-2)14-8-12(20)17-11(19)6-10(18)7-16(17)23-14/h3-8,18-19H,1-2H3 |
| InChIKey | AOLOMULCAJQEIG-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=C(OC)C(OC)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1 |
| LogP | 2.970 (est) |
Description and Uses
5,7-Dihydroxy-3‘,4’-dimethoxyflavone, also known as 4'-Methylchrysoeriol , is a bioactive Flavonoids found in plants such as Eupatorium odoratum. Studies have shown that 4'-Methylchrysoeriol has death receptor 5 promoter-enhancing activity.
4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.
